Thermo Fisher Scientific RNF19A Polyclonal Antibody
Human RNF19A 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody로, WB 및 IHC에 적합. 항원 친화 크로마토그래피로 정제되었으며, 4°C 단기 및 -20°C 장기 보관. 신경퇴행성 질환 연구에 유용.
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Thermo Fisher Scientific RNF19A Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 | View publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RNF19A. Recombinant protein control fragment (Product #RP-93729). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646654 |
Product Specific Information
Immunogen sequence:
EMCTDKNSIF STNTSSDNGL TSISKQIGDF IECPLCLLRH SKDRFPDIMT CHHRSCVDCL
Highest antigen sequence identity:
- Mouse: 98%
- Rat: 93%
Target Information
RNF19A encodes a member of the ring between ring fingers (RBR) protein family. The protein contains two RING-finger motifs and an in-between RING fingers motif. It functions as an E3 ubiquitin ligase localized to Lewy bodies and ubiquitylates synphilin-1, an interacting protein of alpha-synuclein in neurons. This gene may be involved in amyotrophic lateral sclerosis and Parkinson’s disease. Alternative splicing results in multiple transcript variants.
(Information provided by RefSeq, Jul 2013)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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