Thermo Fisher Scientific BAK Monoclonal Antibody (2H9H7)
BAK 단백질을 인식하는 Mouse monoclonal antibody로, Western blot, IHC, Flow cytometry, ELISA에 사용 가능. Human 시료에 반응하며, Protein G로 정제된 1 mg/mL 액상 형태. 단기 4°C, 장기 -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2H9H7 |
| Immunogen | Purified recombinant fragment of human BAK1 (AA: 29–187) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090847 |
Target Information
The protein encoded by this gene belongs to the BCL2 protein family. Members of this family form oligomers or heterodimers and act as anti- or pro-apoptotic regulators involved in various cellular activities. This protein localizes to mitochondria and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, leading to loss of membrane potential and release of cytochrome c. It also interacts with the tumor suppressor P53 after exposure to cell stress.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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