Thermo Fisher Scientific BMP4 Monoclonal Antibody (3C11H8)
BMP4 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC, ICC, Flow cytometry, ELISA 등 다양한 응용에 적합합니다. Human 및 Rat 샘플에 반응하며, Protein G 정제 및 PBS buffer에 0.05% sodium azide를 포함한 액상 형태로 제공됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (IHC) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3C11H8 |
| Immunogen | Purified recombinant fragment of human BMP4 (AA: 277–408) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3093308 |
Target Information
The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family, which is part of the transforming growth factor-beta (TGF-β) superfamily. These proteins are involved in growth and differentiation processes. BMPs were initially identified for their ability to induce endochondral osteogenesis in vivo. BMP4 plays a crucial role in the onset of endochondral bone formation in humans, and reduced expression has been linked to bone disorders such as Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5′ untranslated region results in three transcript variants encoding an identical protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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