Thermo Fisher Scientific Parvalbumin Recombinant Rabbit Monoclonal Antibody (ARC0385)
Parvalbumin 단백질을 인식하는 재조합 토끼 단일클론 항체로, Western blot, IHC, ICC, ELISA 등에 사용 가능. 인간, 생쥐, 랫트 반응성. 고순도 친화 크로마토그래피 정제, 0.5 mg/mL 농도. 연구용 전용 제품.
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Thermo Fisher Scientific Parvalbumin Recombinant Rabbit Monoclonal Antibody (ARC0385)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:6,000 |
| Immunohistochemistry (IHC) | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0385 |
| Immunogen | Recombinant fusion protein containing amino acids 1–180 of human Parvalbumin (PVALB, UniProt P20472) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849162 |
Product Specific Information
Immunogen sequence:
MSMTDLLNAE DIKKAVGAFS ATDSFDHKKF FQMVGLKKKS ADDVKKVFHM LDKDKSGFIE EDELGFILKG FSPDARDLSA KETKMLMAAG DKDGDGKIGV DEFSTLVAES
Target Information
Parvalbumin (PV) is a calcium-binding protein expressed in specific muscle fibers and fast-firing neurons. It belongs to the EF-hand protein family and plays a key role in calcium decay during muscle contraction and relaxation cycles. Parvalbumin expression correlates with muscle relaxation rate and is found in GABAergic interneurons involved in maintaining excitatory/inhibitory balance in the cortex and hippocampus. In ALS patients, parvalbumin immunoreactivity is absent in neuron populations lost early in disease progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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