Thermo Fisher Scientific CD5 (Mantle Cell Lymphoma Marker) Monoclonal Antibody (CD5/54/F6)
CD5 단백질을 인식하는 마우스 단클론 항체로, Mantle Cell Lymphoma 등 T세포 관련 연구에 적합합니다. IHC, ICC/IF, Flow Cytometry 등 다양한 응용이 가능하며, PBS 기반 액상 형태로 제공됩니다. 단백질 A/G 정제 및 보존제 미함유.
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- 921-MSM2-P1ABX
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine, Chicken, Horse, Guinea pig, Human, Non-human primate, Pig, Rabbit, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CD5/54/F6 |
| Immunogen | Recombinant fragment (around aa450–495) of human CD5 protein (intracellular region) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein. It is expressed on all mature T-lymphocytes, most thymocytes, and many T-cell leukemias and lymphomas. CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor regulating T-cell proliferation.
In lymph nodes, CD5 reactivity is mainly observed in T cell areas. It is expressed in 95% of thymocytes and 72% of peripheral blood lymphocytes.
Diseases associated with CD5 dysfunction include thymus cancer and Richter’s Syndrome.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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