Thermo Fisher Scientific CD5 (Mantle Cell Lymphoma Marker) Monoclonal Antibody (C5/473, CD5/54/F6)
CD5 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, T세포 및 일부 B세포 표지에 사용됩니다. IHC, ICC/IF, Flow Cytometry 등 다양한 응용에 적합하며, 단백질 A/G로 정제된 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.5–1 µg/mL |
| Flow Cytometry (Flow) | 0.5–1 µg/10^6 cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine, Human, Rabbit, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C5/473, CD5/54/F6 |
| Immunogen | Human CD5 recombinant protein (C5/473). A synthetic peptide from the intracellular region of human CD5 (CD5/54/F6) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein. It is present on all mature T-lymphocytes, most thymocytes, and many T-cell leukemias and lymphomas. CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor regulating T-cell proliferation. It is found on 95% of thymocytes and 72% of peripheral blood lymphocytes, with primary reactivity in T cell areas of lymph nodes. CD5 expression is associated with various T cell leukemias, lymphomas, and activated T cells. Diseases linked to CD5 dysfunction include thymus cancer and Richter’s Syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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