Thermo Fisher Scientific CD5 (Mantle Cell Lymphoma Marker) Monoclonal Antibody (SPM546)
CD5 단백질을 타겟으로 하는 인간 반응성 마우스 단클론 항체로, T세포 및 림프종 연구에 적합합니다. IHC, ICC/IF, Flow Cytometry 등 다양한 응용에 사용 가능하며, 고순도 Protein A/G 정제 및 액상 형태로 제공됩니다. 연구용 전용 제품입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPM546 |
| Immunogen | Human CD5 recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein. It is present on all mature T-lymphocytes, most thymocytes, and many T-cell leukemias and lymphomas. CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor regulating T-cell proliferation. CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, reactivity is mainly observed in T-cell areas. CD5 expression is associated with various T-cell leukemias, lymphomas, and activated T cells. Diseases related to CD5 dysfunction include thymus cancer and Richter’s Syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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