Thermo Fisher Scientific TNN Polyclonal Antibody
Human TNN 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:200~1:500 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 세포 이동 및 신경 돌기 성장 관련 연구에 적합.
- 카탈로그번호
- PA555411
- 판매단위
- pk
카탈로그
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TNN. Recombinant protein control fragment (Product #RP-94145). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2648789 |
Product Specific Information
Immunogen sequence:
KEQQVTVSHT YKIDVPKSAL VQVDADPQPL SDDGASLLAL GEAREEQNII FRHNIRLQTP QKDCELAGSV QDLLARVKKL EEEMVEMKEQ CSA
Highest antigen sequence identity to the following orthologs:
- Mouse: 84%
- Rat: 85%
Target Information
Extracellular matrix protein that seems to be a ligand for ITGA8:ITGB1, ITGAV:ITGB1 and ITGA4:ITGB1 (PubMed:17909022).
Involved in neurite outgrowth and cell migration in hippocampal explants.
During endochondral bone formation, inhibits proliferation and differentiation of proteoblasts mediated by canonical WNT signaling.
In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells (PubMed:19884327).
Expressed in most mammary tumors, may facilitate tumorigenesis by supporting the migratory behavior of breast cancer cells (PubMed:17909022). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-55411_TNN_Q9UQP3-1_Rabbit.svg)
(이미지 파일명: PA5-55411_TNN_Q9UQP3-1_Rabbit_PDP.jpeg)
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