Thermo Fisher Scientific Glutamine Synthetase Monoclonal Antibody (2D11A2)
Glutamine Synthetase 단백질을 검출하기 위한 Mouse monoclonal antibody. Western blot, IHC, ICC/IF, Flow Cytometry 등 다양한 응용에 적합. 고순도 Protein G 정제, 1 mg/mL 농도, PBS buffer 및 0.05% sodium azide 포함. 연구용으로만 사용.
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Thermo Fisher Scientific Glutamine Synthetase Monoclonal Antibody (2D11A2)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2D11A2 |
| Immunogen | Purified recombinant fragment of human GLUL (aa 2–121) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898443 |
Product Specific Information
This antibody has been tested in indirect ELISA.
Target Information
Glutamine synthase belongs to the glutamine synthetase family. It plays a key role in ammonia incorporation via glutamate dehydrogenase and glutamine synthase. Glutamate serves as both a nitrogen donor and acceptor, central to mammalian nitrogen flow and neurotransmitter regulation. GS activity is tightly controlled by adenylylation and is reduced in the cerebral cortex of Alzheimer’s disease brains and under glucose deprivation conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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