Thermo Fisher Scientific GABBR2 Monoclonal Antibody (5G7F7)
GABBR2 단백질을 인식하는 Mouse IgG2a 단일클론 항체. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 적합. 정제된 단백질 G로 정제되었으며 PBS 버퍼에 0.05% sodium azide 포함. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5G7F7 |
| Immunogen | Purified recombinant fragment of human GABBR2 (aa: 319–483) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898440 |
Product Specific Information
This antibody has been tested in indirect ELISA.
Target Information
GABBR2 is a multi-pass membrane protein belonging to the G-protein coupled receptor 3 family and the GABA-B receptor subfamily. GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, regulating neurotransmitter release and the activity of ion channels and adenylyl cyclase. The GABBR2 subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is functional alone. Allelic variants have been associated with nicotine dependence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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