Thermo Fisher Scientific Cytokeratin 8 Monoclonal Antibody (EP1628Y)
Cytokeratin 8 단백질을 인식하는 토끼 단클론 항체로, IHC(P) 및 ICC/IF에 적합합니다. 인간 시료에 반응하며 CK18 합성 펩타이드 면역원으로 제작되었습니다. 세포 구조 유지 및 신호전달 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | - | View 1 publication |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100 | View 3 publications |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | EP1628Y |
| Immunogen | A synthetic peptide corresponding to residues of the human CK18 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Tissue culture supernatant |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10985243 |
Product Specific Information
MA5-14476 targets Cytokeratin 8 in IHC (P) applications and shows reactivity with Human samples.
The MA5-14476 immunogen is a synthetic peptide corresponding to residues of the human CK18.
Target Information
Cytokeratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12.
Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells.
Cytokeratin 8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells.
This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation.
Mutations in this gene cause cryptogenic cirrhosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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