Thermo Fisher Scientific Peptide Histidine-Methionine Monoclonal Antibody (03)

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

Assay-dependent

-

ELISA (ELISA)

1:2,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

03

Immunogen

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4

Contains

15mM sodium azide

Storage conditions

4° C, store in dark

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_667505

Product Specific Information

ABS 020-03-02 detects PHM in human samples.

ABS 020-03-02 has been successfully used in ELISA procedures. PHM cross-reacts with PACAP (approximately 12%; incomplete, non-parallel inhibition).

NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL

Target Information

Human peptide histidine-methionine (PHM) is a 27-amino-acid peptide belonging to the glucagon-secretin family of peptide hormones. PHM is produced from the same prohormone as VIP, with which it shows considerable sequence homology. The VIP/PHM prohormone is produced by neurons in the central and peripheral nervous systems, often together with acetylcholine. In some situations the effect of the peptides is to reinforce and prolong the effects of neurotransmitter release. Like VIP, PHM is a vasodilator and stimulator of intestinal fluid secretion. High plasma levels of PHM are diagnostic of the corresponding peptide-producing tumor (VIPoma), associated with the watery diarrhea-hypokalemia-achlorhydria syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.