Thermo Fisher Scientific Peptide Histidine-Methionine Monoclonal Antibody (03)

Applications

Immunohistochemistry (IHC)

• Assay-dependent

ELISA

• Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

• ABS 020-03-02 detects PHM in human samples.
• Successfully used in ELISA procedures.
• PHM cross-reacts with PACAP (approximately 12%; incomplete, non-parallel inhibition).
• Concentration may vary by lot (0.85–1.15 mg/mL).

Target Information

Human peptide histidine-methionine (PHM) is a 27-amino-acid peptide belonging to the glucagon-secretin family of peptide hormones.
PHM is produced from the same prohormone as VIP, with which it shows considerable sequence homology.
The VIP/PHM prohormone is produced by neurons in the central and peripheral nervous systems, often together with acetylcholine.
In some situations, the effect of the peptides is to reinforce and prolong the effects of neurotransmitter release.
Like VIP, PHM is a vasodilator and stimulator of intestinal fluid secretion.
High plasma levels of PHM are diagnostic of the corresponding peptide-producing tumor (VIPoma), associated with the watery diarrhea-hypokalemia-achlorhydria syndrome.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.

제품 이미지

(이미지 파일명: ABS_020-03-02_Peptide_Histidine-Methionine_P01282-1_House_mouse.svg, ABS_020-03-02_Peptide_Histidine-Methionine_P01282-1_House_mouse_PDP.jpeg)