Thermo Fisher Scientific SNAP alpha/beta Monoclonal Antibody (16D1)
Thermo Fisher Scientific의 SNAP alpha/beta Monoclonal Antibody (16D1)는 인간 alpha SNAP을 인식하는 마우스 IgG2b 단클론 항체입니다. Western blot에 최적화되어 있으며 rat brain lysate를 양성 대조군으로 추천합니다. 연구용으로만 사용되며 -20°C에서 보관합니다.
- 카탈로그번호
- MA112451
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB)
Tested Dilution
- 1:5,000
Publications
- [참고 문헌 정보 없음]
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 16D1 |
| Immunogen | Recombinant human alpha SNAP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_1087379 |
Product Specific Information
A suggested positive control for this product is rat brain lysate.
Target Information
SNAPs (soluble NSF attachment proteins), acting in concert with SNAREs (SNAP receptors) and the N-ethylmaleimide-sensitive fusion protein (NSF), are required for the fusion of transport vesicles to their target membranes in synaptic transmission, intra-Golgi transport, endosome-to-endosome fusion, and transcytotic vesicles-to-plasma membrane transport.
Vesicle-to-target membrane docking occurs when the vesicle SNARE binds to its cognate target membrane SNARE.
Alpha-SNAP (or beta-SNAP in brain) then binds to this docking complex and mediates the binding of NSF, forming a 20S fusion particle. Once NSF is bound, ATP hydrolysis by NSF initiates the fusion process.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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