Thermo Fisher Scientific SNAP alpha/beta Monoclonal Antibody (16D1)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:5,000

-

Product Specifications

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

16D1

Immunogen

Recombinant human alpha SNAP.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_1087379

Product Specific Information

A suggested positive control for this product is rat brain lysate.

Target Information

SNAPs (soluble NSF attachment proteins), acting in concert with SNAREs ( SNAP receptors) and the N-ethylmaleimide-sensitive fusion protein (NSF) are required for the fusion of transport vesicles to their target membranes in synaptic transmission, intra-Golgi transport, endosome-toendosome fusion and transcytotic vesicles-to-plasma membrane transport. Vesicle-to-target membrane docking (initial contact) occurs when the vesicle SNARE binds to its cognate target membrane SNARE. a-SNAP (or b-SNAP in brain) then binds to this docking complex and mediates the binding of NSF and thus the formation of a 20S fusion particle. It is thought that, once NSF is bound, ATP hydrolysis by NSF initiates the fusion process.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.