
Thermo Fisher Scientific BLNK Monoclonal Antibody (OTI2B2), TrueMAB
BLNK 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI2B2). Western blot에 적합하며 Human, Mouse, Rat 반응성. Lyophilized 형태로 제공되며 PBS buffer에 8% trehalose 포함. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–292 of human BLNK produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882) to ensure carrier-free conditions.
Target Information
B cell linker protein (BLNK) is encoded by the BLNK gene located on human chromosome 10. Also known as SLP‑65 (Src homology 2 domain‑containing leukocyte protein of 65 kDa), BLNK functions as an adaptor protein in the B cell receptor signaling cascade. Deficiency of BLNK leads to improper B cell development. BLNK is phosphorylated by Syk kinase and acts as a scaffold for signaling intermediates such as Vav GEF and Grb2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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