Thermo Fisher Scientific BBS2 Polyclonal Antibody
Thermo Fisher Scientific의 BBS2 폴리클로날 항체로, 인간 BBS2 단백질 중간 영역에 특이적인 합성 펩타이드로 제작됨. Western blot에 0.2–1 µg/mL 농도로 사용 가능. 면역원은 rabbit IgG이며, 액상 형태로 0.5 mg/mL 농도. BBS 단백질 복합체 연구 및 섬모 형성 관련 연구에 적합.
- 카탈로그번호
- PA545024
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1 µg/mL
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human BBS2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2605668 |
Product Specific Information
Peptide sequence:
RGYLPGTAEM RGNLMDTSAE QDLIRELSQK KQNLLLELRN YEENAKAELA
Sequence homology:
Cow: 100%
Dog: 100%
Guinea Pig: 93%
Horse: 100%
Human: 100%
Mouse: 86%
Rabbit: 100%
Rat: 100%
Zebrafish: 100%
Target Information
This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation, and mental retardation.
The proteins encoded by BBS gene family members are structurally diverse, and the similar phenotypes exhibited by mutations in BBS genes are likely due to their shared roles in cilia formation and function. Many BBS proteins localize to basal bodies, ciliary axonemes, and pericentriolar regions of cells.
BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene forms a multiprotein BBSome complex with six other BBS proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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