Thermo Fisher Scientific S100B Recombinant Rabbit Monoclonal Antibody (SC57-02)
S100B 단백질을 인식하는 Thermo Fisher Scientific의 재조합 토끼 단일클론 항체. WB, IHC, ICC, Flow, IP 등 다양한 분석에 사용 가능. 높은 특이성과 재현성을 제공하며, 4°C 또는 -20°C에서 안정적 보관 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:200 |
| Flow Cytometry (Flow) | 1:1,000 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Goat, Human, Mouse, Rat, Zebrafish |
| Host/Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SC57-02 |
| Immunogen | Synthetic peptide within C-terminal human S100 beta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2911579 |
Product Specific Information
- Positive Control: Mouse liver tissue lysates, zebrafish tissue lysates, Hela, N2A, SH-SY5Y, mouse brain tissue
- Subcellular Location: Cytoplasm, Nucleus
Target Information
S100B is a member of the S100 family of proteins containing two EF-hand calcium-binding motifs. These proteins are localized in the cytoplasm and/or nucleus of various cells and regulate cellular processes such as cell cycle progression and differentiation.
S100B may function in neurite extension, melanoma cell proliferation, stimulation of Ca²⁺ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly.
Chromosomal rearrangements and altered expression of this gene are associated with diseases such as Alzheimer’s disease, Down’s syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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