Thermo Fisher Scientific Phospho-Aurora A/B/C (Thr288, Thr232, Thr198) Recombinant Rabbit Monoclonal Antibody (AuroraABC-CC12), APC
Aurora A/B/C 인산화 단백질(Thr288, Thr232, Thr198)을 인식하는 재조합 토끼 단클론 항체로, APC로 표지되어 있습니다. Flow Cytometry에 적합하며, 높은 특이성과 재현성을 제공합니다. 단백질 A/G 정제, PBS+BSA 완충액에 보관됩니다.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | AuroraABC-CC12 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding human Aurora A (Thr288) / Aurora B (Thr232) / Aurora C (Thr198). |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897335 |
Additional Formats
- Unconjugated (MA5-37152)
- FITC (MA5-37154)
- PE (MA5-37153)
- Custom conjugation available upon request
Target Information
Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a key regulator of mitosis. The CPC ensures correct chromosome alignment and segregation, and is required for chromatin-induced microtubule stabilization and spindle assembly. It regulates cytokinesis by phosphorylating multiple substrates including BIRC5, CDCA8, INCENP, and histone H3. Aurora kinases are essential for proper cell division and genomic stability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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