Thermo Fisher Scientific FZD7 Polyclonal Antibody
Human FZD7 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot에 검증됨. 액상 형태이며 1 mg/mL 농도, PBS buffer에 보존. 세포막 및 엔도솜막에 위치한 FZD7 단백질 검출에 적합. 연구용으로만 사용 가능.
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Thermo Fisher Scientific FZD7 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500
Publications: - (No references listed)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within human Frizzled 7 aa 525–574 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.1% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3092355 |
Product Specific Information
- Positive Control: HepG2 cell lysate, 293 cell lysate, 293T cell lysate, human skeletal muscle tissue lysate
- Predicted Band Size: 64 kDa
- Subcellular Location: Cell membrane, Endosome membrane
Target Information
Members of the frizzled gene family encode 7-transmembrane domain proteins that serve as receptors for Wnt signaling proteins.
The FZD7 protein includes:
- N-terminal signal sequence
- 10 cysteine residues typical of Fz family extracellular domains
- 7 transmembrane domains
- Intracellular C-terminal tail with PDZ domain-binding motif
FZD7 gene expression may downregulate APC function and enhance β-catenin-mediated signaling in poorly differentiated human esophageal carcinomas.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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