Thermo Fisher Scientific CXCL11 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1272)
Recombinant Alpaca VHH monoclonal antibody recognizing human CXCL11 (I-TAC). Compatible with ELISA and RIA assays. Produced in CHO cells and purified by metal-chelate chromatography. Supplied in PBS without preservative for research use only.
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Applications
- ELISA (ELISA): Assay-dependent
- Radioimmune Assays (RIA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1272 |
| Immunogen | Recombinant Human CXCL11 / I-TAC |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
Interferon-inducible T-cell alpha chemoattractant (I-TAC), also known as CXCL11 or IP-9, belongs to the CXC chemokine family. It is expressed in peripheral blood leukocytes, pancreas, liver, thymus, spleen, lung, small intestine, placenta, and prostate.
The protein has a molecular weight of 8–11 kDa and plays a role in calcium release regulation and chemotactic response induction in activated T-cells.
CXCL11 is the dominant ligand for CXC receptor-3 (CXCR3) and its gene contains four exons and multiple polyadenylation signals, suggesting cell-specific regulation.
IFN-γ is a potent inducer of CXCL11 transcription, and its expression is upregulated in patients with AIDS, dementia, and multiple sclerosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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