Thermo Fisher Scientific Doublecortin VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1021)
Doublecortin 단백질을 인식하는 알파카 유래 재조합 단일클론 항체로, ELISA에 적합합니다. CHO 세포에서 발현되었으며, 금속 킬레이트 크로마토그래피로 정제되었습니다. PBS 용액 내 보존제 없이 제공되며, 단기 4°C 보관 및 장기 -20°C 보관이 권장됩니다.
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Applications
- ELISA (ELISA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1021 |
| Immunogen | Recombinant Human DCX |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. DCX is a cytoplasmic protein that directs neuronal migration by regulating the organization and stability of microtubules. It contains two doublecortin domains that bind microtubules. This protein also interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, which is important for proper microtubule function in the developing cortex. Mutations in the DCX gene cause X-linked lissencephaly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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