Thermo Fisher Scientific CaV1.3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1882-2181 of human CACNA1D (NP_000711.1).

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.82 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914059

Product Specific Information

Positive test controls include: Rat kidney. The target is usually found in the following locations: Membrane, Multi-pass membrane protein.

Immunogen sequence: RQNYGYYSRY PGRNIDSERP RGYHHPQGFL EDDDSPVCYD SRRSPRRRLL PPTPASHRRS SFNFECLRRQ SSQEEVPSSP IFPHRTALPL HLMQQQIMAV AGLDSSKAQK YSPSHSTRSW ATPPATPPYR DWTPCYTPLI QVEQSEALDQ VNGSLPSLHR SSWYTDEPDI SYRTFTPASL TVPSSFRNKN SDKQRSADSL VEAVLISEGL GRYARDPKFV SATKHEIADA CDLTIDEMES AASTLLNGNV RPRANGDVGP LSHRQDYELQ DFGPGYSDEE PDPGRDEEDL ADEMICITTL

Target Information

CACNA1D is also known as PASNA, SANDD or Cav1. 3. Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.