Thermo Fisher Scientific ERAB Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.5-5 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1-5 µg/mL

-

Immunohistochemistry (PFA fixed) (IHC (PFA))

1-5 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to aa 100-116 of human ERAB protein if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ERAB,uniProtId:Q99714-1,ncbiNodeId:9606,antigenRange:100-116,antigenLength:261,antigenImageFileName:500-10324_ERAB_Q99714-1_Rabbit.svg,antigenImageFileNamePDP:500-10324_ERAB_Q99714-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with proprietary stabilizer

Contains

0.01% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Positive control: U251 cells. Alzheimers brain

Cellular location: Mitochondrion.

Target Information

This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer`s disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.