Thermo Fisher Scientific TRIM21 Polyclonal Antibody
Human TRIM21 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 등 다양한 응용에 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. PBS/glycerol buffer에 보관하며 연구용으로 적합.
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Thermo Fisher Scientific TRIM21 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:25–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein of human TRIM21 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636591 |
Product Specific Information
The antibody detects endogenous levels of total TRIM21 / SSA1 protein.
Target Information
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains — a RING, a B-box type 1, and a B-box type 2 — along with a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein complex, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and nucleus and interacts with autoantigens in patients with Sjögren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants have been described, but only one full-length form has been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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