Thermo Fisher Scientific CARD9 Polyclonal Antibody
CARD9 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 ICC/IF에 적합하며, 인간 CARD9의 521–536번 아미노산 서열을 기반으로 제작됨. NF-κB 신호전달 연구 및 세포사멸 관련 연구용으로 최적화된 고품질 연구용 시약.
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Thermo Fisher Scientific CARD9 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2–3 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide (DRENTTGSDNTDTEGS) corresponding to amino acids 521–536 of human CARD9. Sequence differs from rat origin by two amino acids. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C for short term; for long-term storage, store at −20°C and avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2275097 |
Product Specific Information
- Recommended positive control: PC-3 cell lysate
- Immunogen: Synthetic peptide (DRENTTGSDNTDTEGS) corresponding to amino acids 521–536 of human CARD9.
- Store product as a concentrated solution.
- Centrifuge briefly before opening the vial.
Target Information
The protein encoded by the CARD9 gene belongs to the CARD protein family, characterized by the caspase-associated recruitment domain (CARD). This domain mediates protein interactions involved in activation or suppression of caspase family members, playing a regulatory role in apoptosis. CARD9 interacts with the CARD domain of BCL10, a positive regulator of apoptosis and NF-κB activation, functioning as a molecular scaffold for BCL10 signaling complex assembly. Several alternatively spliced transcript variants exist, though their full-length forms are not clearly defined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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