Thermo Fisher Scientific Diazepam Binding Inhibitor (DBI) Monoclonal Antibody (OTI3A10)

Applications

• Western Blot (WB): 1:500

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

The diazepam binding inhibitor (DBI) is a hormone-regulated protein involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines that modulate signal transduction at type A GABA receptors in brain synapses.
It is conserved from yeast to mammals, with a highly conserved hydrophobic binding domain for medium- and long-chain acyl-CoA esters.
DBI also mediates feedback regulation of pancreatic secretion and postprandial cholecystokinin release, and participates in corticotropin-dependent adrenal steroidogenesis.
Three pseudogenes have been identified on chromosomes 6, 8, and 16. Multiple transcript variants encoding different isoforms exist.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.