Thermo Fisher Scientific proBNP Polyclonal Antibody
마우스 및 랫트 시료에 반응하는 proBNP 폴리클로날 항체입니다. IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능합니다. 단백질 A로 정제된 고순도 항체로, 심부전 관련 바이오마커 연구에 적합합니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from mouse proBNP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
In cardiac tissue, brain natriuretic peptide (BNP) is synthesized as a 134 amino acid precursor (prepro-BNP), which is cleaved by proteases to form a 26 amino acid signal peptide and a 108 amino acid pro-BNP. Proteolytic digestion of pro-BNP results in the formation of a 76 amino acid amino-terminal NT-proBNP and a biologically active 32 amino acid BNP hormone molecule. Both proBNP and NT-proBNP circulate in human plasma and have been proposed as markers for early diagnosis of left ventricular dysfunction as well as prognostic markers of possible cardiac complications in patients with heart failure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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