Thermo Fisher Scientific BAG5 Polyclonal Antibody
BAG5 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 Immunocytochemistry에 사용 가능. 인간 및 마우스에 반응하며 항원 친화 크로마토그래피로 정제됨. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–195 of BAG5 (Uniprot ID: Q9UL15) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.68 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11153783 |
Product Specific Information
- Recommended positive controls: 293T, HeLa, Molt-4, Raji, mouse liver
- Predicted reactivity: Mouse (92%), Rat (91%), Chicken (82%), Chimpanzee (99%), Bovine (93%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
It has been hypothesized that the BAG-5 protein induces the death of nigral neurons through its predicted interaction with hsp70, leading to increased protein aggregation and cell death by disinhibition of hsp70’s anti-apoptotic function. BAG-5 may play an important role in neuronal death mechanisms and could act as a modulator of the hsp70/hsp40 chaperone axis or interact with other BAG-containing proteins via BAG–BAG heterodimerization.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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