Thermo Fisher Scientific Chk2 Polyclonal Antibody
Chk2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 적합. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 인간 CHK2 단백질의 C-말단 영역(500–543)을 면역원으로 사용. 연구용으로만 사용 가능.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 500 and the C-terminus (residue 543) of human Checkpoint Kinase 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
CHEK2 (CHK2) is a serine/threonine kinase involved in the DNA damage checkpoint pathway. Mutations in CHK2 are associated with various cancers. CHK2 is activated by DNA damage and phosphorylates modulators of cell cycle control, including tumor suppressor proteins such as BRCA1. It plays a role in restoring cell survival after DNA damage and is considered a putative tumor suppressor. Mutations in CHK2 have been linked to Li-Fraumeni syndrome and predispositions to sarcomas, breast cancer, and brain tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: A300-620A_CHK2_O96017-1_Rabbit.svg, A300-620A_CHK2_O96017-1_Rabbit_PDP.jpeg)
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