Thermo Fisher Scientific Notch1/MOTC Polyclonal Antibody
Notch1 단백질 검출용 폴리클로날 항체로 Western blot, IHC, ICC, Flow cytometry 및 ELISA에 적합. Rabbit IgG 기반으로 Human, Mouse, Rat 시료 반응성. KLH 결합 합성 펩타이드(aa 2101–2300)로부터 유래. Protein A 정제, 1 mg/mL 농도, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Notch1 (amino acids 2101–2300) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA and 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The Notch gene family encodes transmembrane proteins containing multiple cysteine-rich EGF-like repeats in the extracellular region. In mammals, four Notch genes (Notch1, Notch2, Notch3, Notch4/Int-3) have been identified and are involved in the differentiation of the nervous system and other tissues. Delta and Serrate proteins act as ligands for Notch1. Mature Notch proteins are heterodimeric receptors produced by cleavage of precursor proteins into extracellular (NEC) and transmembrane/intracellular (Ntm) subunits.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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