Thermo Fisher Scientific CSNK1E Monoclonal Antibody (OTI5D4), TrueMAB

Applications and Tested Dilutions

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, another round of desalting is recommended (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

CSNK1E (CK1 epsilon) is a serine/threonine kinase involved in diverse cellular processes such as vesicular trafficking, DNA damage repair, cell cycle progression, and cytokinesis. It phosphorylates key regulatory proteins controlling cell differentiation, proliferation, chromosome segregation, circadian rhythms, and metabolic pathways.
The CK1 family includes seven members (α, β, γ1, γ2, γ3, δ, ε) sharing a conserved kinase domain but differing in N- and C-terminal regions. CK1ε positively regulates Akt, possibly by inhibiting PP2A, and plays an important role in neurodegenerative diseases.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.