
Thermo Fisher Scientific ADH5 Monoclonal Antibody (OTI4H10), TrueMAB
ADH5 단백질을 인식하는 Monoclonal Antibody로, Human, Mouse, Rat에 반응합니다. Western blot에 최적화되어 있으며, 동결건조 형태로 제공됩니다. 고순도 친화 크로마토그래피 정제 방식으로 생산된 연구용 항체입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4H10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–266 of human ADH5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitution: Add 100 µL distilled water to obtain ~1 mg/mL final concentration.
- For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The ADH5 gene encodes a member of the alcohol dehydrogenase family. These enzymes metabolize a wide range of substrates including ethanol, retinol, aliphatic alcohols, hydroxysteroids, and lipid peroxidation products.
The encoded protein forms a homodimer with minimal ethanol oxidation activity but high activity for oxidation of long-chain primary alcohols and S-hydroxymethyl-glutathione.
This enzyme plays a key role in cellular formaldehyde detoxification, preventing irritation and sensitization effects such as lacrymation, rhinitis, and dermatitis.
The human genome also contains several non-transcribed pseudogenes related to this gene.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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