Thermo Fisher Scientific ZGPAT Polyclonal Antibody
Thermo Fisher Scientific의 ZGPAT 폴리클로날 항체는 인간 ZGPAT 단백질의 C-말단 합성 펩타이드에 대해 제작된 Rabbit IgG 항체입니다. Western blot에 적합하며, EGFR 관련 경로 연구 및 전사 억제 기전 분석에 유용합니다. 액상 형태로 제공되며 -20°C에서 장기 보관 가능합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal region of human ZGPAT (UniProt ID: Q8N5A5-1, Antigen range: 484–531) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2884269 |
Product Specific Information
- Immunogen sequence: AGRHSVASAQ LQEKLAGAQR QLGQLRAQEA GLQQEQRKAD THKKMTEF
- Storage guidance:
- Short term: 2–8°C, up to 1 week
- Long term: -20°C, store in small aliquots to prevent freeze-thaw cycles
- Predicted homology:
Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 93%, Sheep: 93%
Target Information
Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival, and migration. Its ability to repress genes of the EGFR pathway suggests it may act as a tumor suppressor, able to suppress breast carcinogenesis.
(Source: UniProt)
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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