Thermo Fisher Scientific ZGPAT Polyclonal Antibody

Applications

• Western Blot (WB)
  Tested Dilution: 0.2–1 µg/mL

Product Specifications

Product Specific Information

• Immunogen sequence: AGRHSVASAQ LQEKLAGAQR QLGQLRAQEA GLQQEQRKAD THKKMTEF
• Storage guidance:
  • Short term: 2–8°C, up to 1 week
  • Long term: -20°C, store in small aliquots to prevent freeze-thaw cycles
• Predicted homology:
  Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 93%, Sheep: 93%

Target Information

Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival, and migration. Its ability to repress genes of the EGFR pathway suggests it may act as a tumor suppressor, able to suppress breast carcinogenesis.
(Source: UniProt)

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.