Thermo Fisher Scientific ZGPAT Polyclonal Antibody

Applications

• Western Blot (WB): 0.2–1 µg/mL

Product Specifications

Product Specific Information

• Immunogen sequence: LLREAVVEGD GILPPLRTEA TESDSDSDGT GDSSYARVVG SDAVDSAQSS
• Storage guidance: For short term use, store at 2–8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted homology: Human: 100%

Target Information

Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival, and migration. Its ability to repress genes of the EGFR pathway suggests it may act as a tumor suppressor and is able to suppress breast carcinogenesis. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.