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Thermo Fisher Scientific NOS3 Monoclonal Antibody (1D12)
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Thermo Fisher Scientific NOS3 Monoclonal Antibody (1D12)

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인간 eNOS 단백질을 인식하는 마우스 단클론 항체로 Western blot, ELISA, in situ PLA에 사용 가능. 고순도 친화 크로마토그래피 정제 제품으로 PBS 용액 형태. -20°C 보관, 연구용으로 적합.

카탈로그번호
H00004846-M04
판매단위
pk
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마지막 업데이트 2025. 08. 04. 오후 05:24
Thermo Fisher Scientific H00004846-M04 NOS3 Monoclonal Antibody (1D12) 100 ug pk판매 단위 pk ·
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Thermo Fisher Scientific · Thermo Fisher Scientific NOS3 Monoclonal Antibody (1D12)

Applications and Tested Dilution

Application Tested Dilution
Western Blot (WB) 1–5 µg/mL
ELISA 3 ng/mL
in situ PLA 1:1200

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Mouse / IgG2a, kappa
Class Monoclonal
Type Antibody
Clone 1D12
Immunogen NOS3 (AAH63294.1, 61 a.a. approximately 160 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 kDa.
Conjugate Unconjugated
Form Liquid
Concentration See Label
Purification Affinity chromatography
Storage Buffer PBS, pH 7.4
Contains No preservative
Storage Conditions -20°C, Avoid Freeze/Thaw Cycles
Shipping Conditions Ambient (domestic); Wet ice (international)

Product Specific Information

Protein sequence:
QPPEGPKFPR VKNWEVGSIT YDTLSAQAQQ DGPCTPRRCL GSLVFPRKLQ GRPSPGPPAP EQLLSQARDF INQYYSSIKR SGSQAHEQRL QEVEAEVAAT

Target Information

Nitric oxide (NO) is an inorganic, gaseous free radical that carries a variety of messages between cells. Vasorelaxation, neurotransmission, and cytotoxicity can all be potentiated through cellular response to NO.
NO production is mediated by members of the nitric oxide synthase (NOS) family, which catalyzes the oxidation of L-arginine to produce L-citrulline and NO.
Three NOS isoforms have been cloned:

  • b/nNOS (type I) – neuronal NOS
  • eNOS (type III) – endothelial NOS
  • iNOS (type II) – inducible NOS

All NOS isoforms contain calmodulin, NADPH, FAD, and FMN binding domains.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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