Thermo Fisher Scientific Phospho-PKC alpha (Thr497) Recombinant Rabbit Monoclonal Antibody (PKCaT497-F1)
Phospho-PKC alpha (Thr497) 특이적 recombinant rabbit monoclonal antibody로 Western blot 및 Flow cytometry에 사용 가능. 인간, 마우스, 랫트 반응성. Protein A/G 정제, PBS/BSA/glycerol buffer. -20°C 보관.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Assay-dependent
Flow Cytometry (Flow)
- 1–1,000 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PKCaT497-F1 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Thr497 of human phospho PKC alpha |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.10% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897296 |
Additional Formats
Target Information
The PKC family of serine/threonine kinases, including PRKCA (PKC alpha), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in structure, tissue distribution, subcellular localization, and substrate specificity. Conventional PKC isoforms (alpha, beta I, beta II, gamma) are Ca²⁺- and phospholipid-dependent. PKC enzymes phosphorylate various protein targets and are involved in diverse signaling pathways, acting as major receptors for phorbol esters. PKC alpha plays roles in cell adhesion, transformation, cell cycle regulation, and cardiac contractility.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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