Thermo Fisher Scientific ATP5EP2 Polyclonal Antibody

Applications

• Western Blot (WB): Tested Dilution 1:2,000

Product Specifications

Target Information

Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane, generated by electron transport complexes of the respiratory chain.
F-type ATPases consist of two structural domains:

• F(1): contains the extramembraneous catalytic core
• F(0): contains the membrane proton channel

These domains are linked by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the F(1) domain is coupled via a rotary mechanism of the central stalk subunits to proton translocation. The rotation of the central stalk against surrounding α₃β₃ subunits leads to hydrolysis of ATP in three separate catalytic sites on the β subunits.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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