Thermo Fisher Scientific MC4R Polyclonal Antibody
Rabbit polyclonal antibody targeting human MC4R (aa 20–34). Validated for Western blot. Affinity purified, supplied in PBS with glycerol and BSA. Suitable for research use only; predicted to cross-react with monkey, cat, and pig.
- 카탈로그번호
- 720295
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide corresponding to Human MC4R (aa 20–34) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 30% glycerol, 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2633246 |
Product Specific Information
These polyclonal antibodies are of rabbit origin, developed by immunizing animals with specific proteins or peptides. The antibody is affinity purified from rabbit sera and tested for functionality in relevant research applications.
This product is intended for Research Use Only and is non-hazardous and non-infectious.
Predicted to react with Monkey, Cat, and Pig.
Target Information
Expression of MC4R has been reported in the brain. Unlike other melanocortin receptors, MC4R is not expressed in the adrenal cortex or melanocytes.
G-protein Coupled Receptors (GPCRs) represent one of the largest families of signaling molecules, sharing a common structure of seven transmembrane helices. They exist in active and inactive forms, and activation by various ligands triggers downstream signaling via G-proteins and effectors.
GPCR regulation and signaling are key areas of pharmacological research, leading to the development of major GPCR-targeted drugs such as Zyprexa and Claritin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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