Thermo Fisher Scientific MC4R Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1–2 µg/mL

Product Specifications

Product Specific Information

These polyclonal antibodies are of rabbit origin, developed by immunizing animals with specific proteins or peptides. The antibody is affinity purified from rabbit sera and tested for functionality in relevant research applications.
This product is intended for Research Use Only and is non-hazardous and non-infectious.
Predicted to react with Monkey, Cat, and Pig.

Target Information

Expression of MC4R has been reported in the brain. Unlike other melanocortin receptors, MC4R is not expressed in the adrenal cortex or melanocytes.
G-protein Coupled Receptors (GPCRs) represent one of the largest families of signaling molecules, sharing a common structure of seven transmembrane helices. They exist in active and inactive forms, and activation by various ligands triggers downstream signaling via G-proteins and effectors.
GPCR regulation and signaling are key areas of pharmacological research, leading to the development of major GPCR-targeted drugs such as Zyprexa and Claritin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.