Thermo Fisher Scientific KLK8 Monoclonal Antibody (OTI14E11), TrueMAB
KLK8 단백질을 인식하는 Mouse monoclonal antibody로 Western blot, IHC, ICC에 사용 가능. Human 시료 반응성. Lyophilized 형태로 제공되며 PBS buffer와 trehalose 포함. 연구용으로 암 및 질환 바이오마커 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI14E11 |
| Immunogen | Full length human recombinant protein of human KLK8 produced in HEK293T cell. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to reach a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Kallikreins are a subgroup of serine proteases involved in various physiological functions. Many kallikreins are implicated in carcinogenesis and may serve as biomarkers for cancer and other diseases.
The KLK8 gene is one of fifteen kallikrein subfamily members located on chromosome 19 and may play a role in proteolytic cascades in the skin and serve as a biomarker for ovarian cancer.
Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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