Thermo Fisher Scientific H3K4me2T6ph Polyclonal Antibody
H3K4me2T6ph 폴리클로날 항체로 히스톤 H3의 Dimethyl Lys4/pT6 변형을 인식. Western blot, IHC, ELISA, IP에 적합. Rabbit IgG 기반으로 고순도 친화 크로마토그래피 정제. 연구용으로만 사용.
- 카탈로그번호
- 600-401-K01
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific H3K4me2T6ph Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (IHC) | 1:50 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | C. elegans, Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Histone H3 [Dimethyl Lys4/pT6] synthetic peptide surrounding the K4me2/pT6 site of human Histone H3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.31 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 30% glycerol, 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.
Stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.
A BLAST analysis suggests cross-reactivity with Human, Mouse, Rat, and C. elegans based on 100% sequence homology. Cross-reactivity with Histone H3 [Dimethyl Lys4/pT6] from other sources has not been determined.
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fiber in eukaryotes. Approximately 146 bp of DNA wraps around a nucleosome, an octamer composed of pairs of the four core histones (H2A, H2B, H3, H4). The chromatin fiber is further compacted by linker histone H1 interacting with DNA between nucleosomes to form higher-order structures.
This gene is intronless and encodes a member of the histone H3 family. Transcripts lack polyA tails and contain a palindromic termination element. Found in a histone cluster on chromosome 1, representing the telomeric copy among duplicated histone genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: 600-401-K01_H3K4me2T6ph_Q71DI3-1_Rabbit.svg, 600-401-K01_H3K4me2T6ph_Q71DI3-1_Rabbit_PDP.jpeg)
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