Thermo Fisher Scientific BNP Polyclonal Antibody
BNP 단백질을 인식하는 Rabbit Polyclonal Antibody로, 인간·마우스·랫에서 반응합니다. WB, IHC(P), ICC/IF 등 다양한 응용에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 심혈관 연구 및 NPPB 단백질 분석에 적합합니다.
- 카탈로그번호
- PA5102596
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NPPB (Accession P16860), corresponding to amino acid residues A10–E60 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851998 |
Product Specific Information
Antibody detects endogenous levels of total NPPB.
Target Information
This gene is a member of the natriuretic peptide family and encodes a secreted protein functioning as a cardiac hormone. The protein undergoes two cleavage events, one intracellularly and another after secretion into the blood. Its biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and maintenance of cardiovascular homeostasis. Elevated levels of this protein in the bloodstream are indicative of heart failure. Mutations have been associated with postmenopausal osteoporosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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