Thermo Fisher Scientific SPDYA Polyclonal Antibody
Thermo Fisher Scientific의 SPDYA Polyclonal Antibody는 인간, 마우스, 랫트에서 반응하며, Western blot, IHC, ICC/IF에 적합합니다. Affinity chromatography로 정제된 고품질 항체로, SPDYA 단백질의 내인성 수준을 검출합니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- PA5102593
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SPDYA (Accession Q5MJ70), corresponding to amino acid residues R197–S247 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851995 |
Product Specific Information
Antibody detects endogenous levels of total SPDYA.
Target Information
Speedy A (SPDYA), also known as SPDY1, Ringo3, or SPY1, is a 313 amino acid nuclear protein belonging to the speedy/ringo family. It is highly expressed in testis and at lower levels in brain, kidney, heart, bone marrow, colon, lung, liver, spleen, and placenta. Speedy A regulates the G1/S phase transition of the cell cycle by binding to and activating Cdc2 p34, Cdk2, and p27. It also mediates cell survival during DNA damage, indicating a role in proper cell cycle progression. Multiple isoforms exist due to alternative splicing. The gene encoding Speedy A is located on human chromosome 2, which encodes over 1,400 genes and comprises nearly 8% of the human genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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