Thermo Fisher Scientific Cdc25A Monoclonal Antibody (DCS-120)
CDC25A 단백질을 인식하는 DCS-120 클론의 Mouse Monoclonal Antibody로, WB, IHC, ICC, IP에 사용 가능. Human, Mouse, Rat 반응성. Recombinant CDC25A를 면역원으로 제작. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | View 6 publications |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | – |
| Immunocytochemistry (ICC/IF) | 5 µg/mL | View 1 publication |
| Immunoprecipitation (IP) | 2 µg/mg protein lysate | – |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | DCS-120 |
| Immunogen | Purified recombinant CDC25A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10980530 |
Product Specific Information
MA5-13794 targets CDC25A in IP, IHC (P), and WB applications and shows reactivity with Human and Rat samples.
The MA5-13794 immunogen is purified recombinant CDC25A.
Target Information
CDC25A is a member of the CDC25 family of phosphatases. Three CDC25 genes are present in human cells: CDC25A, CDC25B, and CDC25C, each functioning at different phases of the cell cycle.
CDC25A is required for progression through G1 and S phases and activates cyclin-dependent kinase CDC2 by removing two phosphate groups.
CDC25A is specifically degraded in response to DNA damage, preventing cells with chromosomal abnormalities from dividing.
CDC25A is an oncogene, although its exact role in oncogenesis has not been fully demonstrated.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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