Thermo Fisher Scientific SF3B4 Polyclonal Antibody
SF3B4 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 다클론 항체. Western blot에 최적화되어 있으며, 인간에 반응하고 다른 종에서도 예측 반응. 합성 펩타이드 면역원 사용, 액상 형태로 -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (AAGPISERNQDAT) corresponding to the N-terminus amino acids of SF3B4 (aa 2–15) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10980167 |
Product Specific Information
- Predicted to react with bovine, canine, mouse, porcine, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
This gene encodes one of four subunits of the splicing factor 3B. The encoded protein cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA within the prespliceosomal complex A. It may also be involved in assembly of the B, C, and E spliceosomal complexes.
In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of splicing factor 3B. It contains two N-terminal RNA-recognition motifs (RRMs), consistent with its role in binding pre-mRNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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