Thermo Fisher Scientific Inhibin alpha Polyclonal Antibody
Inhibin alpha 단백질 검출용 Rabbit Polyclonal 항체로, WB, ELISA, IP 등 다양한 응용에 적합함. 인간, 마우스, 랫트 반응성 보유. 고순도 Affinity chromatography 정제 및 안정적 액상 형태로 제공. 연구용으로만 사용 가능.
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Thermo Fisher Scientific Inhibin alpha Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptides corresponding to amino acid regions 1–50 and 220–270 on the Inhibin alpha gene |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin regulates gonadal stromal cell proliferation negatively and exhibits tumor-suppressor activity. Serum inhibin levels correlate with granulosa-cell tumor size and can serve as a marker for primary and recurrent disease. In prostate cancer, inhibin alpha-subunit gene expression is suppressed and undetectable in poorly differentiated tumor cells. Expression varies across gonadal and extragonadal tissues, suggesting inhibin may function as both a growth/differentiation factor and a hormone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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