Thermo Fisher Scientific Inhibin alpha Polyclonal Antibody
Thermo Fisher Scientific의 Inhibin alpha Polyclonal Antibody는 인간, 마우스, 랫트 반응성을 가지며 다양한 면역실험(WB, IHC, ICC, ELISA 등)에 적합합니다. 합성 펩타이드(aa 125-175)를 면역원으로 사용한 고순도 항체로, 액상 형태이며 안정적인 저장 버퍼를 포함합니다.
- 카탈로그번호
- INBN-112AP
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
| Immunomicroscopy (IM) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 125–175 on human alpha Inhibin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin negatively regulates gonadal stromal cell proliferation and exhibits tumor-suppressor activity. Serum inhibin levels correlate with granulosa-cell tumor size, serving as a marker for primary and recurrent disease. In prostate cancer, inhibin alpha-subunit gene expression is suppressed in poorly differentiated tumor cells. Expression varies among gonadal and extragonadal tissues, suggesting inhibin functions as both a growth/differentiation factor and a hormone.
Note: For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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