
Thermo Fisher Scientific SMOX Polyclonal Antibody
SMOX 단백질을 인식하는 Thermo Fisher Scientific의 토끼 유래 폴리클로날 항체. Western blot, IHC, ICC 등 다양한 응용에 적합. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공. 연구용으로만 사용 가능.
- 카탈로그번호
- PA5100112
- 판매단위
- pk
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Thermo Fisher Scientific SMOX Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SMOX (Accession Q9NWM0), corresponding to amino acid residues V435–T485 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815642 |
Product Specific Information
This antibody detects endogenous levels of total SMOX.
Target Information
Polyamines such as spermine, spermidine, putrescine, and agmatine are polycationic alkylamines involved in numerous cellular functions, including:
- Cell cycle modulation
- Scavenging reactive oxygen species
- Control of gene expression
They also play key roles in neurotransmission by regulating cell-surface receptor activity and intracellular signaling pathways.
The SMOX gene encodes an FAD-containing enzyme that catalyzes the oxidation of spermine to spermidine, producing hydrogen peroxide as a byproduct. Multiple transcript variants encoding different isoenzymes have been identified, some lacking significant oxidase activity on natural polyamine substrates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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