Thermo Fisher Scientific IL-34 Polyclonal Antibody
IL-34 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 1 mg/mL 농도의 액상 형태로 제공되며, PBS 완충액과 0.02% sodium azide를 포함합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.25 µg/mL
- Suggested positive control: Human brain tissue lysate
- Blocking peptide: PEP-0705
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 16 amino acid peptide from near the amino terminus of human IL-34 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | 2–8°C for up to 3 months; for long-term storage, store at -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11155576 |
Product Specific Information
Despite its predicted molecular weight, IL-34 often migrates at a higher molecular weight in SDS-PAGE.
A suggested positive control is human brain tissue lysate.
PA5-20585 can be used with blocking peptide PEP-0705.
Target Information
IL-34 is secreted as a dimeric protein and currently belongs to no known cytokine family.
It signals via the M-CSF Receptor (CSF-1R, CD115), shared with M-CSF.
Although IL-34 has no amino acid sequence homology to M-CSF, they exhibit similarities in secondary structure and overlapping functions.
IL-34 promotes myeloid survival, proliferation, and differentiation, and plays a role in osteoclast formation.
Expression is detected in various tissues, with the highest levels in the spleen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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