Thermo Fisher Scientific Ferritin Heavy Chain Polyclonal Antibody
Ferritin Heavy Chain 단백질을 인식하는 염소 유래 폴리클로날 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 인간 시료에 반응하며, 고순도 액상 형태로 제공됩니다. 철 저장 단백질 연구 및 신경퇴행성 질환 관련 연구에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
- View 2 publications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
- View publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (DKHTLGDSDNES) corresponding to the C-terminus amino acids of FTH1 (aa 172–183) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_11009180 |
Product Specific Information
- Predicted to react with canine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:4000.
Target Information
FTH1 is the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It consists of 24 subunits of heavy and light ferritin chains. Variation in ferritin subunit composition may influence iron uptake and release rates in different tissues. The main role of ferritin is to store iron in a soluble and nontoxic form. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes and alternatively spliced transcript variants, though their biological validity remains undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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