Thermo Fisher Scientific SARS-CoV Spike RBD Recombinant Human Monoclonal Antibody (CR3022-IgA1)
SARS-CoV Spike RBD를 인식하는 인간 단클론 항체 CR3022-IgA1. HEK293F 세포에서 발현된 재조합 항체로 ELISA 등 연구용에 적합. PBS 완충액에 1 mg/mL 농도로 제공되며 4°C에서 보관. 진단용이 아닌 연구용 전용 제품.
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Applications
- ELISA (ELISA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Human / IgA1 |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | CR3022-IgA1 |
| Immunogen | SARS-CoV Spike RBD |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 6.8–7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), also known as 2019-nCoV, causes illnesses ranging from mild cold-like symptoms to severe respiratory distress and death. The CoV Spike (S) protein is crucial for viral attachment, fusion, and entry, and serves as a key target for antibody, entry inhibitor, and vaccine development.
The Spike protein receptor-binding domain (RBD, S-RBD) binds strongly to human and bat ACE2 receptors. SARS-CoV-2 RBD shows significantly higher binding affinity to ACE2 compared to SARS-CoV RBD. The S1 subunit contains this RBD, which specifically interacts with ACE2 receptors on target cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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