ELK Biotechnology Peroxin 1 rabbit pAb
Human 및 Mouse에서 반응하는 Peroxin 1 단백질 검출용 rabbit polyclonal antibody. IHC, IF, ELISA에 적합하며, peroxisome 관련 단백질 연구에 활용. -20°C에서 1년 보관 가능.
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ELK Biotechnology Peroxin 1 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Peroxin 1 rabbit pAb |
| Alternative Names | PEX1; Peroxisome biogenesis factor 1; Peroxin-1; Peroxisome biogenesis disorder protein 1 |
| Applications | IHC; IF; ELISA |
| Recommended Dilutions | Immunohistochemistry: 1/100 - 1/300 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human PEX1 (AA range: 1234–1283) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Gene ID (Human) | 5189 |
| Human Swiss-Prot No. | O43933 |
| Cellular Localization | Cytoplasm; Peroxisome membrane; Associated with peroxisomal membranes |
| Species Reactivity | Human; Mouse |
Background
This gene encodes a member of the AAA ATPase family, a large group of ATPases associated with diverse cellular activities. The protein is cytoplasmic but often anchored to a peroxisomal membrane where it forms a heteromeric complex and plays a role in the import of proteins into peroxisomes and peroxisome biogenesis. Mutations in this gene have been associated with complementation group 1 peroxisomal disorders such as neonatal adrenoleukodystrophy, infantile Refsum disease, and Zellweger syndrome. Alternatively spliced transcript variants have been found for this gene. (RefSeq, Sep 2013)
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